|TUPML054||Microbeam Irradiation System with a Dielectric Laser Accelerator for Radiobiology Research||1664|
Funding: This work was supported by KAKENHI (Grant-in-Aid for Scientific Research)15H03595 and partly supported by NIMS Nanofabrication Platform in Nanotechnology Platform Project sponsored by the MEXT, Japan.
A laser micro-irradiation (LMI) system is widely used in the field of radiobiology because of its acceptably small size. However, damage in a cell nucleus caused by the LMI system does not necessarily simulate a radiation effect. If the laser of the LMI system is replaced with a small-scale 1MeV-class accelerator such as a dielectric laser accelerator (DLA), experiments might be performed under conditions that are more realistic. The desirable configuration of the DLA for a compact micro-beam irradiation system is that laser pulses are transported to a dielectric structure by single-mode optical fibers and the laser energy is accumulated in an accelerator channel. The long and low-intensity laser pulse of 100 MW/cm2, 10ps and a resonator with Q=104 are capable of producing the light intensity of 1 TW/cm2. The long laser pulse, i.e., low laser induced damage threshold intensity, decreases the acceleration gradient to about 1/3 of the ultra-short pulse irradiation of 100 fs. The length of the accelerator at long-laser pulse might be within the allowable range of several cm. The resonator scheme is useful only for the sub-relativistic regime because of the acceleration gradient.
|DOI •||reference for this paper ※ https://doi.org/10.18429/JACoW-IPAC2018-TUPML054|
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